Publications

Trainees are reminded to acknowledge the funding support of NSERC CREATE MATRIX Training Program on their publications.

  1. Tremblay-Gravel M, Fortier A, Baron C, David C, Mehanna P, Ducharme A, Hussin J, Hu Q, Tardif JC, Des Rosiers C, Dupuis J, Ruiz M. Long-Chain Acylcarnitines and Monounsaturated Fatty Acids Discriminate Heart Failure Patients According to Pulmonary Hypertension Status. Metabolites. 2021 Mar 26;11(4):196. doi: 10.3390/metabo11040196. PMID: 33810372.
  2. Chitpin JG, Taylor GP, Xu H, Nguyen TT, Ortega R, Tomlinson JJ, et al. BATL: Bayesian annotations for targeted lipidomics. bioRxiv. 2021:2021.03.18.435788. doi: 10.1101/2021.03.18.435788.
  3. Liaghati A, Pileggi CA, Parmar G, Patten DA, Hadzimustafic N, Cuillerier A, Menzies KJ, Burelle Y, Harper ME. Grx2 Regulates Skeletal Muscle Mitochondrial Structure and Autophagy. Front Physiol. 2021 Mar 5;12:604210. doi: 10.3389/fphys.2021.604210. PMID: 33762963; PMCID: PMC7982873.
  4. Deguise MO, Pileggi C, De Repentigny Y, Beauvais A, Tierney A, Chehade L, Michaud J, Llavero-Hurtado M, Lamont D, Atrih A, Wishart TM, Gillingwater TH, Schneider BL, Harper ME, Parson SH, Kothary R. SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease. Cell Mol Gastroenterol Hepatol. 2021 Feb 2:S2352-345X(21)00025-4. doi: 10.1016/j.jcmgh.2021.01.019. Epub ahead of print. PMID: 33545428.
  5. Dumont AA, Dumont L, Zhou D, Giguère H, Pileggi C, Harper ME, Blondin DP, Scott MS, Auger-Messier M. Cardiomyocyte-specific Srsf3 deletion reveals a mitochondrial regulatory role. FASEB J. 2021 May;35(5):e21544. doi: 10.1096/fj.202002293RR. PMID: 33819356.
  6. Robichaud S, Fairman G, Vijithakumar V, Mak E, Cook DP, Pelletier AR, Huard S, Vanderhyden BC, Figeys D, Lavallée-Adam M, Baetz K, Ouimet M. Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells. Autophagy. 2021 Feb 26:1-19. doi: 10.1080/15548627.2021.1886839. Epub ahead of print. PMID: 33590792.
  7. Pileggi CA, Parmar G, Harper ME. The lifecycle of skeletal muscle mitochondria in obesity. Obes Rev. 2021 May;22(5):e13164. doi: 10.1111/obr.13164. Epub 2021 Jan 13. PMID: 33442950.
  8. Audet-Delage Y, St-Pierre J. Food for Growth: Distinct Nutrient Preferences between Primary Tumors and Metastases. Mol Cell. 2021 Jan 21;81(2):220-222. doi: 10.1016/j.molcel.2020.12.044. PMID: 33482090.
  9. Cairns G, Thumiah-Mootoo M, Burelle Y, Khacho M. Mitophagy: A New Player in Stem Cell Biology. Biology (Basel). 2020 Dec 19;9(12):481. doi: 10.3390/biology9120481. PMID: 33352783; PMCID: PMC7766552.
  10. Dao T, Green AE, Kim YA, Bae SJ, Ha KT, Gariani K, Lee MR, Menzies KJ, Ryu D. Sarcopenia and Muscle Aging: A Brief Overview. Endocrinol Metab (Seoul). 2020 Dec;35(4):716-732. doi: 10.3803/EnM.2020.405. Epub 2020 Dec 23. PMID: 33397034; PMCID: PMC7803599.
  11. Nadeau R, Shahryari Fard S, Scheer A, Hashimoto-Roth E, Nygard D, Abramchuk I, Chung YE, Bennett SAL, Lavallée-Adam M. Computational Identification of Human Biological Processes and Protein Sequence Motifs Putatively Targeted by SARS-CoV-2 Proteins Using Protein-Protein Interaction Networks. J Proteome Res. 2020 Nov 6;19(11):4553-4566. doi: 10.1021/acs.jproteome.0c00422. Epub 2020 Oct 26. PMID: 33103435; PMCID: PMC7640966.
  12. Boardman NT, Migally B, Pileggi C, Parmar GS, Xuan JY, Menzies K, Harper ME. Glutaredoxin-2 and Sirtuin-3 deficiencies impair cardiac mitochondrial energetics but their effects are not additive. Biochim Biophys Acta Mol Basis Dis. 2021 Jan 1;1867(1):165982. doi: 10.1016/j.bbadis.2020.165982. Epub 2020 Sep 28. PMID: 33002579.
  13. Kennedy L, Sandhu JK, Harper ME, Cuperlovic-Culf M. Role of Glutathione in Cancer: From Mechanisms to Therapies. Biomolecules. 2020 Oct 9;10(10):1429. doi: 10.3390/biom10101429. PMID: 33050144; PMCID: PMC7600400.
  14. Patten DA, McGuirk S, Anilkumar U, Antoun G, Gandhi K, Parmar G, Iqbal MA, Wong J, Richardson RB, St-Pierre J, Slack RS, Harper ME. Altered mitochondrial fusion drives defensive glutathione synthesis in cells able to switch to glycolytic ATP production. Biochim Biophys Acta Mol Cell Res. 2021 Jan;1868(1):118854. doi: 10.1016/j.bbamcr.2020.118854. Epub 2020 Sep 11. PMID: 32926942.
  15. Chang L, Zhou G, Soufan O, Xia J. miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology. Nucleic Acids Res. 2020 Jul 2;48(W1):W244-W251. doi: 10.1093/nar/gkaa467. PMID: 32484539; PMCID: PMC7319552.
  16. Nikpay M, Lau P, Soubeyrand S, Whytock KL, Beehler K, Pileggi C, Ghosh S, Harper ME, Dent R, McPherson R. SGCG rs679482 Associates With Weight Loss Success in Response to an Intensively Supervised Outpatient Program. Diabetes. 2020 Sep;69(9):2017-2026. doi: 10.2337/db20-0219. Epub 2020 Jun 11. PMID: 32527767.
  17. Rose M, Filiatreault A, Guénette J, Williams A, Thomson EM. Ozone increases plasma kynurenine-tryptophan ratio and impacts hippocampal serotonin receptor and neurotrophic factor expression: Role of stress hormones. Environ Res. 2020 Jun;185:109483. doi: 10.1016/j.envres.2020.109483. Epub 2020 Apr 5. PMID: 32278163.
  18. Pelletier AR, Chung YE, Ning Z, Wong N, Figeys D, Lavallée-Adam M. MealTime-MS: A Machine Learning-Guided Real-Time Mass Spectrometry Analysis for Protein Identification and Efficient Dynamic Exclusion. J Am Soc Mass Spectrom. 2020 Jul 1;31(7):1459-1472. doi: 10.1021/jasms.0c00064. Epub 2020 Jun 17. PMID: 32510216.
  19. Anilkumar U, Khacho M, Cuillerier A, Harris R, Patten DA, Bilen M, Iqbal MA, Guo DY, Trudeau LE, Park DS, Harper ME, Burelle Y, Slack RS. MCL-1Matrix maintains neuronal survival by enhancing mitochondrial integrity and bioenergetic capacity under stress conditions. Cell Death Dis. 2020 May 5;11(5):321. doi: 10.1038/s41419-020-2498-9. PMID: 32371858; PMCID: PMC7200794.
  20. Islam H, Ma A, Amato A, Cuillerier A, Burelle Y, Simpson CA, Quadrilatero J, Gurd BJ. Fiber-specific and whole-muscle LRP130 expression in rested, exercised, and fasted human skeletal muscle. Pflugers Arch. 2020 Mar;472(3):375-384. doi: 10.1007/s00424-020-02359-4. Epub 2020 Feb 17. PMID: 32065259.
  21. McGuirk S, Audet-Delage Y, St-Pierre J. Metabolic Fitness and Plasticity in Cancer Progression. Trends Cancer. 2020 Jan;6(1):49-61. doi: 10.1016/j.trecan.2019.11.009. Epub 2020 Jan 3. PMID: 31952781.
  22. Ruiz M, Cuillerier A, Daneault C, Deschênes S, Frayne IR, Bouchard B, Forest A, Legault JT; LSFC Consortium, Vaz FM, Rioux JD, Burelle Y, Des Rosiers C. Lipidomics unveils lipid dyshomeostasis and low circulating plasmalogens as biomarkers in a monogenic mitochondrial disorder. JCI Insight. 2019 Jul 25;4(14):e123231. doi: 10.1172/jci.insight.123231. PMID: 31341105; PMCID: PMC6675547.
  23. Cuillerier A, Burelle Y. Hybrid Clear/Blue Native Electrophoresis for the Separation and Analysis of Mitochondrial Respiratory Chain Supercomplexes. J Vis Exp. 2019 May 19;(147). doi: 10.3791/59294. PMID: 31157764.
  24. Sebaa R, Johnson J, Pileggi C, Norgren M, Xuan J, Sai Y, Tong Q, Krystkowiak I, Bondy-Chorney E, Davey NE, Krogan N, Downey M, Harper ME. SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1. Mol Metab. 2019 Jul;25:35-49. doi: 10.1016/j.molmet.2019.04.008. Epub 2019 Apr 17. PMID: 31060926; PMCID: PMC6601363.
  25. Alecu I, Bennett SAL. Dysregulated Lipid Metabolism and Its Role in α-Synucleinopathy in Parkinson's Disease. Front Neurosci. 2019 Apr 11;13:328. doi: 10.3389/fnins.2019.00328. PMID: 31031582; PMCID: PMC6470291.
  26. Cadete VJJ, Vasam G, Menzies KJ, Burelle Y. Mitochondrial quality control in the cardiac system: An integrative view. Biochim Biophys Acta Mol Basis Dis. 2019 Apr 1;1865(4):782-796. doi: 10.1016/j.bbadis.2018.11.018. Epub 2018 Nov 22. PMID: 30472159.
  27. Chitpin JG, Awdeh A, Perkins TJ. RECAP reveals the true statistical significance of ChIP-seq peak calls. Bioinformatics. 2019 Oct 1;35(19):3592-3598. doi: 10.1093/bioinformatics/btz150. PMID: 30824903; PMCID: PMC6761936.
  28. Xu H, Boucher FR, Nguyen TT, Taylor GP, Tomlinson JJ, Ortega RA, Simons B, Schlossmacher MG, Saunders-Pullman R, Shaw W, Bennett SAL. DMS as an orthogonal separation to LC/ESI/MS/MS for quantifying isomeric cerebrosides in plasma and cerebrospinal fluid. J Lipid Res. 2019 Jan;60(1):200-211. doi: 10.1194/jlr.D089797. Epub 2018 Nov 9. PMID: 30413651; PMCID: PMC6314254.
  29. Picard M, Prather AA, Puterman E, Cuillerier A, Coccia M, Aschbacher K, Burelle Y, Epel ES. A Mitochondrial Health Index Sensitive to Mood and Caregiving Stress. Biol Psychiatry. 2018 Jul 1;84(1):9-17. doi: 10.1016/j.biopsych.2018.01.012. Epub 2018 Feb 3. PMID: 29525040; PMCID: PMC6014908.
  30. Kizilay Mancini O, Lora M, Cuillerier A, Shum-Tim D, Hamdy R, Burelle Y, Servant MJ, Stochaj U, Colmegna I. Mitochondrial Oxidative Stress Reduces the Immunopotency of Mesenchymal Stromal Cells in Adults With Coronary Artery Disease. Circ Res. 2018 Jan 19;122(2):255-266. doi: 10.1161/CIRCRESAHA.117.311400. Epub 2017 Nov 7. PMID: 29113965.
Scroll Up